Post-exposure management of bloodborne pathogen exposure. bloodborne Post-exposure management of bloodborne pathogen exposure. Lesson Content 0% Complete 0/3 Steps The first step in post-exposure management is to wash the affected area with soap and water. The exposed individual should report the exposure to their supervisor or occupational health department. Prophylactic treatment may be necessary to prevent infection, including hepatitis B immunoglobulin and antiviral medications. Previous Lesson Back to Course Next Lesson